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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DVL1
All Species:
16.97
Human Site:
S517
Identified Species:
46.67
UniProt:
O14640
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14640
NP_004412.2
695
75187
S517
N
S
G
S
S
G
T
S
D
Q
D
T
L
A
P
Chimpanzee
Pan troglodytes
Q5IS48
670
72833
S492
N
S
G
S
S
G
A
S
D
Q
D
T
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001105770
731
78423
D527
D
G
S
S
G
A
S
D
Q
D
T
L
A
P
L
Dog
Lupus familis
XP_546713
700
75601
S517
N
S
G
S
S
G
A
S
D
Q
D
T
L
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P51141
695
75332
S517
N
S
G
S
S
G
A
S
D
Q
D
T
L
A
P
Rat
Rattus norvegicus
Q9WVB9
695
75429
S517
N
S
G
S
S
G
A
S
D
Q
D
T
L
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422756
833
90624
G636
H
D
H
D
G
S
S
G
A
S
D
Q
D
T
L
Frog
Xenopus laevis
Q6DKE2
717
78751
G513
N
D
H
D
G
S
S
G
T
S
D
Q
D
T
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51140
623
68898
L466
I
K
H
T
V
N
K
L
T
F
S
E
Q
C
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
60.5
95.2
N.A.
94.8
95.1
N.A.
N.A.
55.5
65.9
N.A.
N.A.
40.4
N.A.
N.A.
N.A.
Protein Similarity:
100
96.2
71.9
96.7
N.A.
96.6
96.9
N.A.
N.A.
67.5
78
N.A.
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
20
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
20
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
45
0
12
0
0
0
12
56
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
12
23
0
23
0
0
0
12
56
12
78
0
23
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
12
56
0
34
56
0
23
0
0
0
0
0
0
0
% G
% His:
12
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
12
56
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
56
% P
% Gln:
0
0
0
0
0
0
0
0
12
56
0
23
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
56
12
67
56
23
34
56
0
23
12
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
12
0
23
0
12
56
0
23
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _